Data for the role of the replenishment of synaptic vesicles in epilepsy has been published by Kevin Staley at the University of Colorado-Boulder. He used an experimental system very similar to the one I used (see data). Dr. Staley published a mathematical model for epileptiform electrical behavior in brain slices from rats. More
Finally, 470 bp of the nDNA intron of the phosphoenolpyruvate carboxykinase (PEPCK) gene were amplified and sequenced with primers from A. Turmelle (personal communication). ... however, both occur in Colorado and there are individuals from Boulder County, Colorado, in each of these phylogroups . More
"Phosphoenolpyruvate Carboxykinase (GTP)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. More
The kidney-specific chromatin structure of the phosphoenolpyruvate carboxykinase (PEPCK) gene was examined and compared to that of the liver. Kidney nuclear extracts were found to lack a liver-enriched factor, pepA, that binds to HSS A, a distal More
Address for reprint requests and other correspondence: D. L. Allen, Dept. of Integrative Physiology, Univ. of Colorado, Boulder, Campus Box 354, Boulder, CO 80309 (e-mail: [email protected]). Search for more papers by this author, More
Alterations in Key Gluconeogenic Regulators With Age and Endurance Training Deborah B. Horn, Deborah A. Podolin, Jacob E. Friedman, David A. Scholnick, and Robert S. Mazzeo The purpose of the present investigation was to examine changes in six potential regulators of hepatic gluconeogenesis with normal aging and endurance training: fructose 2,6-bisphosphate (F 2,6-P2), mitochondrial and ... More
(PEPCK 335–351, lower panel) to MHC class II (I-Ab) molecule and their respective binding energies. Fig. S3. Multiple amino acid sequence alignment of PEPCK from various Leishmania genus. Fig. S4. Comparison of amino acid sequences of Leishmania-specific TCRα chain. Fig. S5. Direct ex vivo cytokine profile of PEPCK 335–351–specific CD4 ... More
Department of Integrative Physiology, University of Colorado, Boulder, Colorado Submitted 10 May 2010; accepted in final form 25 June 2010 Allen DL, Cleary AS, Lindsay SF, Loh AS, Reed JM. Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice. More
Introduction. Familial hypertrophic cardiomyopathy (HCM) is a disorder affecting approximately 0.2% of the population and is the leading cause of sudden death in young people in the United States (Redwood et al, 1999).The R403Q mutation, located in the actin‐binding domain of cardiac myosin heavy chain, is linked to a severe clinical phenotype (Seidman & Seidman, 2001), and transgenic mice ... More
Horizon Discovery drives the application of gene editing and gene modulation to enable world-leading academic institutes, pharmaceutical and biotechnology companies, as well as clinical diagnostic laboratories, to identify the genetic drivers behind human disease, develop and validate diagnostic workflows, and deliver new therapies for precision medicine. More
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